Join a Research Study

A research study tests or evaluates treatments—such as new or current medications, behavior treatments, medical equipment, clinical therapies, procedures, or programs—to determine if they are safe and effective.

Why Should I Participate?

If you are looking for a way to stop smoking, participating in a research study may be right for you. People in research studies can receive new treatments before they reach the public. You may also help other smokers by contributing to research that could lead to new treatment options in the future.

Who Conducts Research Studies?

There are countless smoking cessation research studies going on around the world to help determine the best, most effective ways to help people stop smoking and stay quit. A number of the studies being run in the United States are funded by the National Institutes of Health (NIH) and carried out by researchers outside of NIH, usually at universities or medical schools.

Where Can I Learn More About Research Studies?

To learn more about smoking research studies currently recruiting around the world, visit the clinicaltrials.gov database.

Studies Currently Recruiting

Development of the smoking cessation app “Smiling instead of Smoking”

If you smoke cigarettes on some days (but not daily), and are interested in using a smoking cessation app to help you do so, you may be eligible to participate in our research study. We’ll provide smoking cessation support via our newly developed smartphone app and will compensate you for your time (up to $434). To set up a phone-screen call and get started with this study, please call 617-724-3129 or email sis@mgh.harvard.edu. Please note that our app currently is only available for Android smartphones.

Six-Month Outcomes of a Mobile Smoking Cessation Program

Location: Nationwide

Want to quit smoking? Not even? Either way, we’d like to talk. Be among the first to use a new program designed to help people learn about their smoking and—if they want—quit. During this six-month research study, participants will give breath samples with a personal sensor and use a smartphone app to interact with a personal coach, do brief games and activities, and track their smoking.

The study is entirely remote (no office visits or clinic appointments). Participants will earn up to $315 for completing the study, with compensation every one to four weeks, after completing short questionnaires.

This study is open to adult smokers aged 18-65 in the continental United States who own and use a smartphone.

For further info, please visit: my.pivot.co/participate

UCSF Cut2Quit Study

Want to cut down on smoking before completely quitting? The Cut2Quit Study can help you with that!

Researchers at UCSF are developing a program that allows smokers to track and gradually reduce their smoking before quitting for good.

If you are 18 years and older, regularly smoke cigarettes, and use an iPhone, you may be eligible to participate in the Cut2Quit Study. Study participants will receive nominal cash incentives for completing surveys and a free gift valued at $125!

For more information and to sign up for the study, please visit: ​http://cut2quit.eurekaplatform.org/NCI

Multimodal Neuroimaging Genetic Biomarkers of Nicotine Addiction Severity

Study Location: Baltimore, MD (Local Recruitment)

Quitting smoking is hard. Let us help you through it. If you are 18-60 years old and ready to quit smoking, we need you for a research study on nicotine dependence at the National Institute on Drug Abuse in Baltimore. The study’s treatment plan is customized to your individual needs and includes free nicotine replacement combined with one-on-one counseling. This is a program that offers a research/treatment combination.

  • Earn up to $1690 for completing the study
  • Receive compensation after each study visit
  • Receive an MRI image of your brain on a t-shirt
  • Evening and weekend study appointments available

We want you to succeed. Call today to see if you qualify.



UCLA Smoking Cessation Study

Study Location: In-person visits in the Los Angeles area

Are you ready to quit smoking? The Addictions Research Laboratory in the UCLA Department of Psychology is looking for smokers, between the ages of 21 and 65 who drink alcohol regularly, to participate in a research study. Participants will receive 14 weeks of FREE treatment with effective smoking cessation medication and will be asked to attend study visits at the UCLA campus in Westwood.

Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers

Study Location: In-person visits in the Chicago area

This research study offers two different forms of counseling, along with an FDA-approved medication or matched placebo, designed to help people who have experienced depressed mood or loss of interest to quit smoking.

As part of the study, participants receive eight sessions of free individual smoking cessation treatment delivered by trained therapists, along with 12 weeks of varenicline (Chantix) or placebo. Participants may earn up to $205 for completing all aspects of the study.

If you are interested in learning more about the study and seeing if you are eligible to participate, please call 1-877-236-7487, email our study team at hitsmanlab@northwestern.edu, or visit http://tinyurl.com/smoking-depression.

Extended Varenicline Treatment for Cigarette Smoking Among Cancer Patients

Study Location: In-person visits in the Chicago area

Quitting smoking is hard, especially for people who are fighting cancer, but Northwestern University's and University of Pennsylvania's Quit for Health program can help. Quit for Health is now offering a clinical research study funded by the National Cancer Institute that is evaluating a new smoking cessation intervention tailored to cancer patients and survivors.

Eligible smokers will receive seven sessions of smoking cessation counseling and receive varenicline, a U.S. Food and Drug Administration (FDA)-approved smoking cessation medication – all at no charge. Participants receive $10 for each completed session and an additional $10 for travel.

If you are over the age of 18, diagnosed with cancer within the last five years, and interested in learning more about the study and our specialized smoking cessation treatment, please call (1-877-236-7487) or email Michael Maloney michael.maloney2@northwestern.edu.


Study location: University of California, Irvine

Are you looking to quit smoking, but need help? Apply for the Tweet2Quit program today! You will receive a complimentary 8-week supply of nicotine patches & gum, as well as the opportunity to earn up to $60 by completing short surveys. Our program can help motivate you to quit smoking using the power of a peer-based support group, all from the convenience of your phone. This study is open to smokers aged 21 to 59 in the continental United States who plan to quit smoking. You must also have a mobile phone with unlimited texting, use some sort of social media regularly, and be willing to tweet with your quit smoking group daily. For further info please click: http://tweet2quit.merage.uci.edu/

mSMART Smoking Study

Study location: Nationwide

Department of Psychiatry at Duke University is conducting a research study on how you take Chantix® (varenicline) medication to quit smoking. You will receive electronic pill bottles called “MEMS Cap” to use while you take your medication. You will need to have an Android or iOS smartphone. If you have recently started taking or planning to take Chantix® (varenicline) to quit smoking, then make the most of your quit attempt by joining the mSMART Smoking Study.

To learn more about the study or volunteer to participate, please contact:

Dr. Jennifer Stevenson
(919) 684 5403


More For You

Are you a health professional? Help smokers quit with these evidence-based resources from Smokefree.gov.
Talking to an expert about quitting smoking may be the support you need to see it through.
No single quit smoking method is right for everyone. Learn more to decide which ones might be right for you.